for graphics related work u need a beefy cpu and a gpu.. and after effects uses cuda/open cl accelerator so u definitely need a beefy gpu, gtx 1070 + 7700k/1700x/1800x combo is a must.. if u can buy ryzen for this purpose it's a better choice than Intel's current consumer lineup...
u don't need quadro or firepro gpus I repeat u don't need them unless u want to burn ur money for minimal to no performance improvements

most productivity software don't use double precision so u don't need them and they are ¤¤¤¤¤¤¤** expensive...
don't buy AMD bcz cuda will annihilate opencl... and most render engines work better with cuda, even some gpu render engines don't even support opencl....