EA confirmed today that they will announce new title from DICE and BioWare at E3 2013. Could this mean a reveal of Mirror's Edge 2 & Mass Effect 4? Mirror's Edge is the biggest franchise of DICE beside Battlefield. A sequel is speculated in development for a long time.
On the other hands, BioWare has confirmed the development of Mass Effect 4 with Frostbite 3 some time ago. BioWare already announced their upcoming title Dragon Age 3: Inquisition which is also using Frostbite 3.